2010年

Ellis J, Baum C, Benvenisty N, Mostoslavsky G, Okano H, Stanford WL, Porteus, M, and Sadelain M: Benefit of utilizing gene-modified iPSCs for clinical applications. Cell Stem Cell 7(4):429-430, 2010 [PubMed]

Nishimoto Y, Okano H : New insight into cancer therapeutics: induction of differentiation by regulating the Musashi/Numb/Notch pathway. Cell Res. 20(10):1083-1085, 2010. [PubMed]

Yamamoto-Hino M, Kanie Y, Awano W, Aoki-Kinoshita KF, Yano H, Nishihara S, Okano H, Ueda R, Kanie O and Goto S:
Identification of genes required for neural-specific glycosylation using functional genomics. PLoS Genet. 6(12):e1001254, 2010. [PubMed]

Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H : Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes. Molecular Brain 3(1):31, 2010. [PubMed]

Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida Y, Ogura T, Otsuka T, Okano H and Sawamoto K.: Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain. Stem Cells 28(11):2017-2026, 2010. [PubMed]

Wang X-Y, Penalva LOF, Yuan H, R. Linnoila RI, Lu J, Okano H and Glaze RI: Musashi1 regulates breast tumor initiating cell proliferation and is a prognostic indicator of poor survival. Molecular Cancer 9(1):221, 2010. [PubMed]

Hirota Y, Meunier A, Huang S, Shimozawa T, Yamada O, Kida YS, Inoue M, Ito T, Kato H, Sakaguchi M, Sunabori T, Nakaya MA, Nonaka S, Ogura T, Higuchi H, Okano H, Spassky N, Sawamoto K.:Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development. 137(18):3037-3046, 2010. [PubMed]

Aihara Y, Hayashi Y, Hirata M, Ariki N, Shibata S, Nagoshi N, Nakanishi M,Ohnuma K, Warashina M, Michiue T, Uchiyama H, Okano H, Asashima M, Kusuda Furue M.: Induction of neural crest cells from mouse embryonic stem cells in a serum-free monolayer culture. Int J Dev Biol. 54(8-9):1287-1294, 2010. [PubMed]

Kuwako KI, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara SI,Tessier-Lavigne M, Okano HJ, Okano H: Neural RNA-Binding Protein Musashi1
Controls Midline Crossing of Precerebellar Neurons through Posttranscriptional Regulation of Robo3/Rig-1 Expression. Neuron. 67(3):407-421, 2010. [PubMed]

Kaneko N, Marin O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL and Sawamoto K.: New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron 67(2): 213-223, 2010 [PubMed]

Tomioka I, Maeda T, Shimada H, Kawai K, Okada Y, Igarashi H, Oiwa R, Iwasaki T, Aoki M, Kimura T, Shiozawa S, Shinohara H, Kuronuma H, Yagihashi C, Suemizu H, Sasaki E, Okano H.: Generating Induced Pluripotent Stem Cells from Common Marmoset (Callithrix jacchus) Fetal Liver Cells Using Defined Factors Including Lin28. Genes to Cells 15(9):959-969, 2010. [PubMed]

Sato T, Shimazaki T, Naka H, Fukami S, Satoh Y, Okano H, Lax I, Schlessinger J, Gotoh N.: FRS2alpha Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells. Stem Cells.28(9):1661-1673, 2010. [PubMed]

Tsuji O, Miura K, Okada Y, Fujiyoshi K, Nagoshi N, Kitamura K, Kumagai G, Mukaino M, Nishino M, Tomisato S, Higashi H, Ikeda E, Nagai T, Kohda K, Takahashi K, Okita K, Katoh H, Matsuzaki Y, Yuzaki M, Toyama Y, Nakamura M, Yamanaka S, Okano H.: Therapeutic effect of the appropriatelly evaluated ‘safe’ iPS cells for spinal cord injury. Proc.Natl.Acad.Sci.USA. 107(28):12704-12709, 2010 [PubMed]

Doi Y, Shinzawa N, Fukumoto S, Okano H, Kanuka H.: ADF2 regulates transformation of the ookinete and sporozoite in malaria parasite development. Biochem Biophys Res Commun. 397(4):668-672, 2010 [PubMed]

Mukaino M, Nakamura M, Yamada O, Okada S, Morikawa S, Renault-Mihara F, Iwanami A, Ikegami T, Ohsugi Y, Tsuji O, Katoh H, Matsuzaki Y, Toyama Y, Liu M, Okano H.: Anti IL-6 receptor antibody administered to the injured spinal cord accelerates repair process by modifying inflammatory cell recruitment. Exp. Neurol. 224(2):403-414, 2010 [PubMed]

Masuda H, Matsuzaki Y, Hiratsu E, Ono M, Nagashima T, Kajitani T, Arase T, Uchida H, Asada H, Ito M, Yoshimura Y, Maruyama T, Okano H.: Side population in human endometrium exhibits stem cell-like properties: implication for endometrial regeneration and endometriosis. PLoS ONE 5(4):e10387, 2010 [PubMed]

Okano H.: Neural stem cells and strategies for the regeneration of the central nervous system. Proc. Jpn. Acad., Ser. B. 86(4):438-450, 2010. [PubMed]

Suzuki S, Namiki J, Shibata S, Matsuzaki Y, Okano H.: The neural stem/progenitor cell marker Nestin is expressed in proliferative endothelial cells, but not in mature vasculature. J.Histochem. and Cytochem. 58(8): 721-730, 2010 [PubMed]

Contini M, Lin B, Kobayashi K, Okano H, Masland RH, Raviola E.: Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina. J. Comp. Neurol. 518(11) 2035-50, 2010 [PubMed]

Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H.: von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development. 137(9) 1563-71 [PubMed]

Sakaguchi M, Imaizumi Y, Shingo T, Tada H, Hayama K, Yamada O, Morishita T, Kadoya T, Uchiyama N, Shimazaki T, Kuno A, Poirier F, Hirabayashi J, Sawamoto K, Okano H.: Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction. J Neurochem 113(6): 1516-1524, 2010. [PubMed]

Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H, Nakashima K.: BMP-induced REST regulates the establishment and maintenance of astrocytic identity. J. Cell Biol., 189(1) 159-70 [PubMed]

Shimizu H, Mori A, Yamada T, Ishikawa A, Okano H, Takeda J, Yozu R.: Regional spinal cord cooling using a countercurrent closed-lumen epidural catheter. Ann. Thorac. Surg., 89(4) 1312-3 [PubMed]

Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S. : The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury. Am. J. Pathol. 176(5): 2352-2366, 2010 [PubMed]

Kanki H, Shimabukuro MK, Miyawaki A, Okano H.: “Color Timer” mice: visualization of neuronal differentiation with fluorescent proteins. Mol Brain., 2010 Feb 2;3:5 [PubMed]

Shindo A, Nakamura T, Matsumoto Y, Kawai N, Okano H, Nagao S, Itano T, Tamiya T.: Seizure suppression in amygdala-kindled mice by transplantation of neural stem/progenitor cells derived from mouse embryonic stem cells. Neurol. Med. Chir.,50(2):98-105, 2010. [PubMed]

Yamane J, Nakamura M, Iwanami A, Sakaguchi M, Katoh H, Yamada M, Momoshima S, Miyao S, Ishii K, Tamaoki N, Nomura T, Okano HJ, Kanemura Y, Toyama Y, Okano H.: Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets. J. Neurosci. Res. 88(7):1387-93, 2010 [PubMed]

Kiyokage E, Pan YZ, Shao Z, Kobayashi K, Szabo G, Yanagawa Y, Obata K, Okano H, Toida K, Puche AC, Shipley MT.: Molecular identity of periglomerular and short axon cells. J Neurosci. 30(3):1185-96, 2010 [PubMed]

Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, Sawamoto K.: Subventricular Zone-Derived Neural Progenitor Cells Migrate Along a Blood Vessel Scaffold Toward the Post-Stroke Striatum.
Stem cells
. 28(3): 545-554, 2010
[PubMed]

Kanazawa H, Ieda M, Kimura K, Arai T, Kawaguchi-Manabe H, Matsuhashi T, Endo J, Sano M, Kawakami T, Kimura T, Monkawa T, Hayashi M, Iwanami A, Okano H, Okada Y, Ishibashi-Ueda H, Ogawa S, Fukuda K.: Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents.
J Clin Invest. 120(2): 408-421, 2010 [PubMed]

Oki K, Kaneko N, Kanki H, Imai T, Sawamoto K, Suzuki N, Okano H: Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia. Neurosci. Res., 66(4) 390-5, 2010. [PubMed]

Wakabayashi K, Fujioka M, Kanzaki S, Okano HJ, Shibata S, Yamashita D, Masuda M, Mihara M, Ohsugi Y, Ogawa K, Okano H.: Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea. Neurosci. Res., 66(4):345-52, 2010 [PubMed]

Terashima M, Kobayashi M, Motomiya M, Inoue N, Yoshida T, Okano H, Iwasaski N, Minami A, Matsuoka I.: Analysis of the expression and function of BRINP family genes during neuronal differentiation in mouse embryonic stem cell-derived neural stem cells. J. Neurosci. Res., 88(7):1387-93, 2010 [PubMed]

Tada H, Okano HJ. Takagi H, Shibata S, Matsumoto M, Yao I, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H. : Kspot, a novel ubiquitin ligase, regulates synaptic activity. J. Biol. Chem. 285(6):3840-9, 2010. [PubMed]

Ishii S., Okada Y, Kadoya T, Matsuzaki Y, Shimazaki T, Okano H. : Stromal cell-secreted factors promote the survival of ES cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways. J. Neurosci. Res., 88(4):722-34, 2010 [PubMed]

Tao O, Shimazaki T, Okada Y, Naka H, Kohda K, Yuzaki M, Mizusawa H, Okano H.: Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells. J Neurosci Res. 88(2):234-247, 2010. [PubMed]

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