Outline of the Work

Questions

What is neural stem cell?

How are neural stem cells generated?
　How is the development of the central nervous system regulated?
　How is it maintained?

Key research required resolving these questions

Screening of genes regulating the development, differentiation and maintenance of neural stem cells, and understanding their interactions and regulatory mechanisms.

Major tools for these key studies

Genetically modified animals
　ES cells

Possibilities in the near future

It would be possible to reproduce and artificially control the development and matured central nervous system in vitro.
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It would be possible to apply these to develop methods for the prevention and treatment of diseases of the central nervous system.

Contact

Takuya Shimazaki（shimazak＠sc.itc.keio.ac.jp）