Namiki J., Suzuki S., Shimazaki T., Okano H.: Effects of Inflammatory Cytokines on CNS Regeneration from Endogenous CNS Stem Cells.
Neurotrauma Research 17: 50-56, 2005.
Kanemura Y., Mori H., Nakagawa A., Islam MO., Kodama E., Yamamoto A., Shofuda T., Kobayashi S., Miyake J., Yamazaki T., Hirano S., Yamasaki M., Okano H.: In vitro screening of exogenous factors for human neural stem/progenitor cell proliferation using measurement of total ATP content in viable cells.
Cell Transplantation 14: 673-682, 2005.
Inaji M., Yoshizaki T., Okauchi T., Maeda J., Nagai Y., Nariai T., Ohno K., Ando K., Okano H., Obayashi S., Suhara T.: In vivo PET measurements with [11C]PE2I to evaluate fetal mesencephalic transplantation to unilateral 6-OHDA-lesioned rats. Cell Transplantation 14: 655-663, 2005.
Inaji M., Okauchi T., Ando K., Maeda J., Nagai Y., Yoshizaki T., Okano H., Nariai T., Ohno K., Obayashi S., Higuchi M., Suhara T.: Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats.
Brain Res. 1064: 136-145, 2005.
Iijima T., Imai T., Kimura Y., Bernstein A., Okano HJ., Yuzaki M., Okano H. : Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA.
Proc. Natl. Acad. Sci. USA 102: 17190-17195, 2005.
Yamamoto S., Yoshino I., Shimazaki T., Murohashi M., Lax I., Okano H., Shibuya M., Sclegginger J., Gotoh N.: Essential role of Shp2-binding sites on FRS2{alpha} for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells.
b>Proc. Natl. Acad. Sci. USA 102: 15983-15988, 2005.
Ikegami T., Nakamura M., Yamane J., Katoh H., Okada S., Iwanami A., Watanabe W., Ishii K., Kato F., Fujita H., Takahashi T., Toyama Y., Okano H.: Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances their migration and axonal regeneration after rat spinal cord injury.
Eur. J. Neurosci. 22: 3036-3046, 2005.
Suzuki T., Izumoto S., Wada K., Fujimoto Y., Maruno M., Yamasaki M., Kanemura Y., Shimazaki T., Okano H., Yoshimine T.: Inhibition of glioma cell proliferation by neural stem cell factor.
J. Neurooncol. 74: 233-239, 2005.
Kanuka H., Kuranaga E., Hiratou T., Okano H., Miura M.: Drosophila Caspase transduce Shaggy/GSK-3beta activity in neural precursor development.
EMBO J. 24: 3793-3806, 2005.
Kanuka H., Hiratou T., Igaki T., Kanda H., Kuranaga E., Sawamoto K., Aigaki T., Okano H., Miura M.: Gain-of-function screen identifies a role of the Sec61a transcolon in Drosophila postmitotic neurotoxcity.
Biochimica et Biophysica Acta 1726: 225-237, 2005.
Asai R, Okano H, Yasugi S.: Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse.
Dev. Growth Diff. 47: 501-510, 2005
Tomita Y., Wakamatsu Y., Shibuya I., Matsumura K., Kawaguchi H., Hisaka Y., Matsuzaki Y., Osumi N., Ogawa S., Okano H., Fukuda K.: Cardiac neural crest cells as dormant multipotent stem cells, identified as side population cells.
J. Cell Biol. 170: 1135-1146, 2005.
Kohyama J., Tokunaga A., Fujita Y., Miyoshi H., Nagai T., Miyawaki A., Nakao K., Mastuzaki Y., Okano H.: Visualization of spatio-temporal activation of Notch signaling: live monitoring and significance in neural development.
Dev. Biol. 286: 311-325, 2005.
Okada S., Ishii K., Yamane J., Iwanami A., Ikegami T., Iwamoto Y., Nakamura M., Miyoshi H., Okano HJ., Contag CH., Toyama Y., Okano H.:In vivo imaging of engrafted neural stem cells: its application inevaluating the optimal timing of transplantation for spinal cord injury.
FASEB J. 19:1839-1841, 2005.
Matsumoto T., Okamoto R.., Yajima T., Mori T., Okamoto S., Ikeda Y., Mukai M., Yamazaki M., Oshima S., Tsuchiya K., Nakamura T., Kanai T.,Okano H., Inazawa J., Hibi T., Watanabe M.: Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.
Gastroenterology 128:1851-1867, 2005.
Jomphe C., Bourque MJ., Fortin GD., St-Gelais F., Okano H., Kobayashi K., Trudeau LE.: Use of TH-EGFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture.
J. Neurosci. Methods. 146: 1-12, 2005.
Tonchev AB., Yamashima T., Sawamoto K., Okano H.: Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia.
J. Neurosci. Res. 81:776-788, 2005.
Okano H., Okada S., Nakamura M., Toyama Y.: Neural Stem Cells and Regeneration of Injured Spinal Cord.
Kidney International 68: 1927-1931, 2005.
Nakamura M., Okada S., Toyama Y., Okano H.: Role of IL-6 in spinal cord injury in a mouse model.
Clinical Reviews in Allergy & Immunology In Press, 2005.
Sahara M., Sata M., Matsuzaki Y., Tanaka K., Morita T., Hirata Y., Okano H., Nagai R.: Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury.
Stem Cells 23: 874-878, 2005.
Hishikawa K., Miura S., Nakanishi A., Shibata K., Matsuzaki Y., Marumo T., Hayashi M., Nakaki T., Okano H., Fujita T.: Musculin/MyoR is Expressed in Kidney Side Population Cells and Can Regulate Their Function.
J. Cell Biol. 169: 921-928, 2005.
Nakamura M., Okano H., Toyama Y., Dai HN., Bregman BS.: Transplantation of embryonic spinal cord-derived neural stem cells support growth of suprapinal projections and functional recovery after spinal cord injury in naonate rat.
J. Neurosci. Res. 81: 457-468, 2005.
Mori A. Ueda T., Shimizu H., Yoshitake A., Hachiya T., Onoguchi K., Takakura H., Yoshitake M., Taguchi S., Cho Y., Inoue S., Kabei N., Okano H., Yozu R., Sasaki T.: An Epidural Cooing Catheter Protects the Spinal Cord Against Ischemic Injury in Pigs. Annals of Thoracic Surgery 80: 1829-1833, 2005.
Islam MO., Kanemura Y., Tajria J., Mori H., Kobayashi S., Miyake J., Hara M., Yamasaki M., Okano H.: Characterization of ABC transporter, ABCB1 expressed in human neural stem/progenitor cells.
FEBS Lett. 579: 3473-3480, 2005.
Sasaki E., Hanazawa K., Kurita R., Akatsuka A., Yoshizaki T., Ishii H., Tanioka Y., Ohnishi Y., Suemizu H., Sugawara A., Tamaoki N., Izawa K., Nakazaki Y., Hamada H., Suemori H., Nakatsuji N., Okano H., Tani K.: Establishment of Novel Embryonic Stem Cell Lines Derived from the Common Marmoset (Callithrix jacchus).
Stem Cells 23: 1304-1313, 2005.
Yuasa S., Itabashi Y., Koshimizu U., Tanaka T., Sugimura K., Fukami S., Itabashi Y., Hattori F., Shimazaki T., Ogawa S., Okano H., Fukuda K.: Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells.
Nature Biotech. 23: 607-611, 2005.
Yoshimi K., Ren Y.-R., Seki T., Yamada M., Hayakawa H., Ooizumi H., Onodera M., Saito Y., Maruyama S., Okano H., Mizuno Y., Mochizuki H.: Possibility of neurogenesis in substantia nigra of parkinsonian brain.
Ann. Neurol. 58: 31-40, 2005.
Matsuda Y., Wakamatsu Y., Kohyama J., Okano H., Fukuda K., Yasugi S.: Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development.
Development 132: 2783-2793, 2005.
Yamashita T., Sawamoto K., Suzuki S., Suzuki N., Adachi K., Kawase T., Mihara M., Ohsugi Y., Abe K., Okano H.: Blockade of IL-6 signaling aggravates ischemic cerebral damage in mice.
J. Neurochem. 94: 459-468, 2005.
Uchida K., Momiyama T., Okano H., Yuzaki M., Koizumi A., Mine Y., Kawase T.: Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin.
Neurosci. Res. 53: 276-286, 2005.
Kambara H., Okano H., Chiocca A., Saeki Y.: An oncolytic HSV1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals, even when symptomatic from a brain tumor.
Cancer Research 65: 2832-2839, 2005.
Akasaka Y., Saikawa Y., Fujita K., Kubota T., Ishii T., Okano H., Kitajima M.: Expression of a candidate marker for progenitor cells, Musashi-1, in the proliferative regions of human antrum and its decreased expression in intestinal metaplasia.
Histopathology 47: 348-356, 2005.
Akamatsu W., Fujiwara H., Mitsuhashi T., Yano M., Shibata S., Hayakawa Y., Okano HJ., Sakakibara S., Takano H., Takano T., Takahashi T., Noda T., Okano H.: The RNA-binding protein HuD regulates neuronal cell identity and maturation.
Proc.Natl.Acad.Sci.USA 102: 4625-4630, 2005.
Sakatani T., Kaneda A., Iacobuzio-Donahue CA., Carter MG., Witzel SB., Okano H., Ko, MSH., Ohlsson R., Longo DL., Feinberg AP.: Loss of imprinting of Igf2 alter intestinal maturation and tumorigenesis in mice.
Science 307: 1976-1978, 2005.
Okano H., Kawahara H., Toriya M., Nakao K., Shibata S., Imai T.: Function of RNA binding protein Musashi-1 in stem cells.
Exp. Cell Res. 306: 349-356, 2005.
PignatelliA., Kobayashi K., Okano H., Belluzzi O.: Functional responses of dpominergic neurons in the mouse olfactory bulb.
J. Physiol. 564: 501-514, 2005.
Kitagawa A., Nakayama T., Takenaga M., Matsumoto K., Tokura Y., Ohta Y., Ichinohe M., Yamaguchi Y., Suzuki N., Okano H., Igarashi R.: Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo.
Biochem Biophys Res Commun. 328:1051-1057, 2005.
Yoda A., Kouike H., Okano H., Sawa H.: Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans
Development 132: 1855-1893, 2005.
Tamura M., Nakamura M., Ogawa Y., Toyama Y., Miura M., Okano H.: Targeted expression of anti-apoptotic protein, p35, in oligodendrocytes reduces delayed demyelination and functional impairment after spinal cord injury.
Glia 51: 312-321, 2005.
Suzuki K., Fukui H., Kayahara T., Sawada M., Seno H., Hiai H., Kageyama R., Okano H., Chiba T.: Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine.
Biochem. Biophys. Res. Commun. 328: 348-352, 2005.
Islam MO., Kanemura Y., Tajria J., Mori H., Kobayashi S., Hara M., Yamasaki M., Okano H., Miyake J.: Functional expression of ABCG2 transporter in human neural stem/progenitor cells.
Neurosci. Res. 52:75-82, 2005
Yano M., Okano HJ., Okano H.: Involvement of Hu and hnRNP K in neuronal differentiation through p21 mRNA post-transcriptional regulation.
J. Biol. Chem. 280: 12690-12699, 2005.
Crespel A., Rigau V., Coubes P., Rousset MC., de Bock F., Okano H., Baldy-Moulinier M., Bockaert J., Lerner-Natoli M.: Increased neurogenesis in human temporal lobe epilepsy: evidence for a new neurogenis area, the fissura hippocanpi.
Neurobiology of Disease 19: 436-450, 2005.
Sasaki T., Iwata S., Okano HJ., Urasaki Y., Hamada J., Tanaka H., Dang NH., Okano H., Morimoto C.: Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia..
Stroke 36: 2457-2462, 2005.
Iwanami A., Yamane J., Katoh H., Nakamura M., Momoshima S., Ishii H., Tanioka Y., Tamaoki N., Nomura T., Toyama Y., Okano H.: Establishment of Graded Spinal Cord Injury Model in a Non-human Primate: the Common Marmoset.
J. Neurosci. Res. 80: 272-181, 2005.
Iwanami A., Kakneko S., Nakamura M., Kanemura Y., Mori H., Kobayashi S., Yamasaki M., Momoshima S., Ishii H., Ando K., Tanioka Y., Tamaoki N., Nomura T.,Toyama Y., Okano H.: Transplantation of human neural stem/progenitor cells promotes functional recovery after spinal cord injury in common marmoset.
J. Neurosci. Res. 80: 182-190, 2005.
Hishikawa K., Marummo T., Miura S., Nakanishi A., Matsuzaki Y., Shibata K., Kohike H., Komori T., Hayashi M., Nakaki T., Nakauchi H., Okano H. , Fujita T.: Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16.
Biochem. Biophys. Res. Com. 328: 288-291, 2005.
Nagato M., Heike T., Kato T., Yamanaka Y., Yoshimoto M., Shimazaki T., Okano H., Nakahata T.: Prospective characterization of neural stem cells by flow cytometry analysis using combination of the surface markers.
J. Neurosci. Res. 80: 456-466, 2005.
Uemura O., Okada Y., Ando H., Guedj M., Higashijima S., Shimazaki T., Chino N., Okano H. and Okamoto H.: Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor neuron and sensory neuron-specific expression.
Dev. Biol. 278: 587-606, 2005.
Hirota Y., SawamotoK., Takahashi K., Ueda R., Okano H.: The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster.
Dev. Genes Evol. 212:90-96, 2005.
Sakaguchi M., Sawamoto K., Shimazaki T., Kitamura T., Shibuya A., Okano H.: A method for gene transfer, single isolation and in vitro assay for neural stem cells.
Inflammation and Regeneration 25: 50-54, 2005.
Suzuki S., Yamashita T., Tanaka K., Hattori H., Sawamoto K., Okano H., Suzuki N.: Activation of cytokine signaling through Leukemia Inhibitory Factor Receptor (LIFR)/gp130 attenuates ischemic brain injury in rats.
J. Cerebral Blood Flow and Metabolism 25:685-693, 2005.
Clarke RB., Spence K., Anderson E., Howell A., Okano H., Potten CS.: A putative human breast stem cell population is enriched for steroid receptor-positive cells.
Dev. Biol. 277:443-456, 2005.
Iwanami A., Ogawa Y., Nakamura M., Kaneko S., Sawamoto K., Okano HJ., Toyama Y., Okano H.: ‘Neural stem/progenitor cell transplantation for spinal cord repair; optimal timing of transplantation.’ Principle of Molecular Neurosurgery. Prog. Neurol. Surg. (eds. Freese A., Simone FA., Leone P., Janson C.), Basel, Karger, 18: 104-123, 2005.
Nakamura Y., Yamamoto M., Miyado K., Okano HJ., Fukagawa R., Higaki K., Yamasaki M., Okano H. : A novel marker for Purkinje cells, KIAA0864 protein. An analysis based on a monoclonal antibody HFB-16 in developing human cerebellum.
J. Histochem. Cytochem. 53: 423-430, 2005.
